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Transcriptome sequencing identifies key pathways and genes involved in gastric adenocarcinoma.
Zhang W, Liu S, Zhan H, Yan Z, Zhang G. Zhang W, et al. Mol Med Rep. 2018 Oct;18(4):3673-3682. doi: 10.3892/mmr.2018.9370. Epub 2018 Aug 9. Mol Med Rep. 2018. PMID: 30106143 Free PMC article.
The present study aimed to investigate the key pathways and genes associated with gastric adenocarcinoma via transcriptome sequencing. Five pairs of gastric adenocarcinoma tissue and normal tumor-adjacent tissue were harvested. ...Furthermore, 15 DEGs significantly …
The present study aimed to investigate the key pathways and genes associated with gastric adenocarcinoma via transcriptome sequencing …
p38delta/MAPK13 as a diagnostic marker for cholangiocarcinoma and its involvement in cell motility and invasion.
Tan FL, Ooi A, Huang D, Wong JC, Qian CN, Chao C, Ooi L, Tan YM, Chung A, Cheow PC, Zhang Z, Petillo D, Yang XJ, Teh BT. Tan FL, et al. Int J Cancer. 2010 May 15;126(10):2353-61. doi: 10.1002/ijc.24944. Int J Cancer. 2010. PMID: 19816939 Free article.
In this study, we have identified a p38 MAP kinase, p38delta (also known as MAPK13 or SAPK4) as a protein that is upregulated in CC relative to HCC and to normal biliary tract tissues. ...
In this study, we have identified a p38 MAP kinase, p38delta (also known as MAPK13 or SAPK4) as a protein that is upregulated in CC r …
Sympathetic nerve infiltration promotes stomach adenocarcinoma progression via norepinephrine/beta2-adrenoceptor/YKL-40 signaling pathway.
Qi YH, Yang LZ, Zhou L, Gao LJ, Hou JY, Yan Z, Bi XG, Yan CP, Wang DP, Cao JM. Qi YH, et al. Heliyon. 2022 Dec 21;8(12):e12468. doi: 10.1016/j.heliyon.2022.e12468. eCollection 2022 Dec. Heliyon. 2022. PMID: 36593854 Free PMC article.
OBJECTIVE: This study aimed to address the status, role, and mechanism of sympathetic nerve infiltration in the progression of stomach adenocarcinoma (STAD). METHODS: Sympathetic nerve and its neurotransmitter NE, beta-ARs, and associated signaling molecules in the STAD ti …
OBJECTIVE: This study aimed to address the status, role, and mechanism of sympathetic nerve infiltration in the progression of stomach ad …
Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma.
Goto Y, Shinjo K, Kondo Y, Shen L, Toyota M, Suzuki H, Gao W, An B, Fujii M, Murakami H, Osada H, Taniguchi T, Usami N, Kondo M, Hasegawa Y, Shimokata K, Matsuo K, Hida T, Fujimoto N, Kishimoto T, Issa JP, Sekido Y. Goto Y, et al. Cancer Res. 2009 Dec 1;69(23):9073-82. doi: 10.1158/0008-5472.CAN-09-1595. Epub 2009 Nov 3. Cancer Res. 2009. PMID: 19887624
We performed high-throughput methylation analysis covering 6,157 CpG islands in 20 MPMs and 20 lung adenocarcinomas. Newly identified genes were further analyzed in 50 MPMs and 56 adenocarcinomas via quantitative methylation-specific PCR. ...Among the DNA hypermethy …
We performed high-throughput methylation analysis covering 6,157 CpG islands in 20 MPMs and 20 lung adenocarcinomas. Newly identified …
Proteomics analysis to reveal biological pathways and predictive proteins in the survival of high-grade serous ovarian cancer.
Xie H, Wang W, Sun F, Deng K, Lu X, Liu H, Zhao W, Zhang Y, Zhou X, Li K, Hou Y. Xie H, et al. Sci Rep. 2017 Aug 29;7(1):9896. doi: 10.1038/s41598-017-10559-9. Sci Rep. 2017. PMID: 28852147 Free PMC article.
We found that biosynthesis of amino acids was the main biological pathway with the best predictive performance (AUC = 0.900). A panel of three proteins, namely EIF2B1, PRPS1L1 and MAPK13 were selected as potential predictive proteins and the risk score consisting of these …
We found that biosynthesis of amino acids was the main biological pathway with the best predictive performance (AUC = 0.900). A panel of thr …